OGT and SNAP91

Number of citations of the paper that reports this interaction (PubMedID 8063760)
13

Data Source:
HPRD (in vitro)

		OGT	SNAP91
Description		O-linked N-acetylglucosamine (GlcNAc) transferase	synaptosome associated protein 91
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Mitochondrial Membrane Protein-containing Complex Cell Projection	Plasma Membrane Clathrin-coated Pit Synaptic Vesicle Clathrin-coated Vesicle Presynaptic Membrane Extrinsic Component Of Presynaptic Endocytic Zone Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific) Protein O-GlcNAc Transferase Activity	SNARE Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Kinase Binding Clathrin Heavy Chain Binding
	Biological Process	Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Viral Process Protein Processing Protein Deubiquitination Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K27 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Cold-induced Thermogenesis	Endocytosis Vesicle Budding From Membrane Protein Transport Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Clathrin Coat Assembly Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis
Pathways		HATs acetylate histones UCH proteinases	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Electrodermal activity ( 25387706) Macular thickness ( 30535121) Schizophrenia ( 28991256 29483656 30285260)
Interacting Genes		22 interacting genes: CSNK2A1 CSNK2B GSK3B HCFC1 HIRA MAPT MTDH NUP62 NUP62CL OGA PHC3 PSG1 SIN3A SNAP91 SP1 SRF TAB1 TAB3 TRAK1 TRAK2 UBC YES1	9 interacting genes: AP2A2 AP2B1 DNAJC5 EPS15 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B
Entrez ID		8473	9892
HPRD ID		02222	06391
Ensembl ID		ENSG00000147162	ENSG00000065609
Uniprot IDs		O15294	B7Z2N2 E9PDG8 H0UI15 O60641
PDB IDs		1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4CDR 4GYW 4GYY 4GZ3 4GZ5 4GZ6 4N39 4N3A 4N3B 4N3C 4XI9 4XIF 5BNW 5C1D 5HGV 5LVV 5LWV 5NPR 5NPS 5VIE 5VIF 6E37 6EOU 6IBO 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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