SSBP2 and LDB1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		SSBP2	LDB1
Description		single stranded DNA binding protein 2	LIM domain binding 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex
	Molecular Function	Single-stranded DNA Binding	RNA Polymerase II Activating Transcription Factor Binding Transcription Corepressor Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organism Development Neuron Differentiation Regulation Of Cell Migration Regulation Of DNA-templated Transcription, Elongation Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Focal Adhesion Assembly Regulation Of Hematopoietic Stem Cell Differentiation
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Anorexia nervosa ( 21079607) Bipolar disorder ( 31043756) Glioblastoma ( 22472174)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Pulse pressure ( 30578418)
Interacting Genes		8 interacting genes: AP3B1 CDK6 EWSR1 IL36RN LDB1 LDB2 PIN1 TOM1	27 interacting genes: ATXN1 CTDSP1 DNMT3L ESR1 IRAK3 ISL1 LHX2 LHX3 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP UPF1
Entrez ID		23635	8861
HPRD ID		09577	09144
Ensembl ID		ENSG00000145687	ENSG00000198728
Uniprot IDs		A0A087X159 P81877	Q86U70
PDB IDs		6IWV	2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?
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