PRAME and ZNF408

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

		PRAME	ZNF408
Description		preferentially expressed antigen in melanoma	zinc finger protein 408
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane	Nucleus
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Positive Regulation Of Cell Proliferation Cell Differentiation Regulation Of Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)
Interacting Genes		9 interacting genes: ELOB ELOC FBXO7 RARA RBX1 STK19 UBC XRN2 ZNF408	38 interacting genes: ATRN CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 GIPC1 GPATCH2L HOXA5 HOXB9 ID3 KHDRBS3 KRTAP4-12 LDOC1 LSM2 MDFI MIF PDE4DIP PDLIM4 PRAME PRNP PRPF31 RALYL SAP30BP THAP1 TOP3B UPF2 ZBTB8A ZBTB9 ZNF212 ZNF330 ZNF331 ZNF792
Entrez ID		23532	79797
HPRD ID		05820	18338
Ensembl ID		ENSG00000185686	ENSG00000175213
Uniprot IDs		A0A024R1E6 B7Z7K8 B7Z986 B7ZAT0 P78395	B4DXY4 Q9H9D4
PDB IDs
Enriched GO Terms of Interacting Partners?
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