PRAME and ELOB

Number of citations of the paper that reports this interaction (PubMedID 21822215)
18

Data Source:
BioGRID (affinity chromatography technology, pull down)

		PRAME	ELOB
Description		preferentially expressed antigen in melanoma	elongin B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane	Nucleoplasm Cytosol VCB Complex Cul2-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Elongin Complex
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Apoptotic Process Positive Regulation Of Cell Proliferation Cell Differentiation Regulation Of Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Retinoic Acid Receptor Signaling Pathway	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Viral Process Protein Ubiquitination Post-translational Protein Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein-containing Complex Assembly
Pathways			Formation of RNA Pol II elongation complex Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Vif-mediated degradation of APOBEC3G RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation Neddylation Regulation of expression of SLITs and ROBOs Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: ELOB ELOC FBXO7 RARA RBX1 STK19 UBC XRN2 ZNF408	28 interacting genes: ACSM5 ASB2 ASB8 CAPN1 CCP110 CDR2 CEBPE DGAT2 ELOA ELOA2 ELOA3 ELOC EPOR GHR GPS2 HOXC10 LRRC41 PRAME RACK1 RNF7 SMG1 SOCS1 SOCS3 SOCS6 STC2 USP33 VHL ZYG11B
Entrez ID		23532	6923
HPRD ID		05820	02874
Ensembl ID		ENSG00000185686	ENSG00000103363
Uniprot IDs		A0A024R1E6 B7Z7K8 B7Z986 B7ZAT0 P78395	A0A384MDL3 Q15370
PDB IDs			1LM8 1LQB 1VCB 2C9W 2IZV 2JZ3 2MA9 3DCG 3ZKJ 3ZNG 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 4BKS 4BKT 4N9F 4W9C 4W9D 4W9E 4W9F 4W9G 4W9H 4W9I 4W9J 4W9K 4W9L 4WQO 5BO4 5LLI 5N4W 5NVV 5NVW 5NVX 5NVY 5NVZ 5NW0 5NW1 5NW2 5T35 6BVB 6C5X 6FMI 6FMJ 6FMK 6GFX 6GFY 6GFZ 6GMN 6GMQ 6GMR 6GMX 6HAX 6HAY 6HR2 6I4X 6I5J 6I5N 6I7Q 6I7R 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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