FOS and CREB5

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 381
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

FOS

CREB5

Description Fos proto-oncogene, AP-1 transcription factor subunit cAMP responsive element binding protein 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Periodontal microbiota ( 22699663)
  • Adolescent idiopathic scoliosis ( 31417091)
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (memory) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728)
  • Anxiety in major depressive disorder ( 24047446)
  • Asthma (childhood onset) ( 31036433)
  • Atrial fibrillation ( 30061737 29892015)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Blond vs. brown/black hair color ( 30531825)
  • Breast cancer ( 29059683)
  • Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
  • Crohn's disease ( 23128233)
  • Diabetic retinopathy ( 21441570)
  • Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Granulocyte count ( 27863252)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Hand grip strength ( 29691431)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 28552196)
  • Lymphocyte percentage of white cells ( 27863252)
  • Monocyte percentage of white cells ( 27863252)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 29403010 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Neutrophil percentage of white cells ( 27863252)
  • Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Pulse pressure ( 27841878 30578418)
  • Serum thyroid-stimulating hormone levels ( 25436638)
  • Smoking behaviour (cigarettes smoked per day) ( 31217584)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White blood cell count ( 29403010 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 114 interacting genes: ANP32E APP AQP1 ARFGAP1 ARL6IP4 ATF2 ATF3 ATF4 ATF7 ATP5ME BATF BCL3 CABP1 CARM1 CCND1 CEBPA CEBPE CEBPG CENPO CFAP57 CLU COPS4 CREB5 CREBBP CSNK2A1 CSNK2A2 CYTH4 DDIT3 DNMT3L EEF1D ELK1 ELK4 EPHB2 ETS1 ETS2 FHL3 GAMT GATA4 GLB1 GNG11 GRHPR GTF2E2 GTF2F1 GTF2F2 HNF1A HSPA1A JUN JUNB JUND KDM2A KDM2B LMNA LMO3 LUZP4 MAF MAFB MAFF MAP1B MAP3K7 MAPK1 MAPK3 MAPK7 MITF MTERF4 NACA NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NEFM NELFB NFATC3 NFKB1 OPTN PIN1 PML POLR2E PRKAA2 PRKACA PSMC5 RB1 RELA RPS6KA1 RPS6KA2 RPS6KA4 RUNX1 RUNX2 SCHIP1 SET SIRT1 SMAD3 SMARCD1 SPI1 SRA1 STAT1 SUMO1 SUMO2 SUMO3 SUMO4 TAF1 TBP TRO TSC22D3 TSPAN2 UBE2D1 UBE2I UBE2L3 UBR1 USF1 USF2 VDR XBP1 ZNF133 40 interacting genes: ADAMTSL4 ATF2 COL8A1 EFEMP2 FOS FOSL1 FOSL2 JUN KIFC3 KRT15 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LGALS13 MDFI MGAT5B MTUS2 NOTCH2NLA RBPMS RGS20 RIMBP3 SPOP SPRY1 SPRY2 TRAF2 TRIM23 TRIP6 TSGA10
Entrez ID 2353 9586
HPRD ID 01275 09896
Ensembl ID ENSG00000170345 ENSG00000146592
Uniprot IDs P01100 Q6FG41 Q02930
PDB IDs 1A02 1FOS 1S9K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?