CREB5 and KRTAP9-4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CREB5	KRTAP9-4
Description		cAMP responsive element binding protein 5	keratin associated protein 9-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Extracellular Exosome	Cytosol Keratin Filament
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated	Keratinization
Pathways			Keratinization
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 31417091) Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Airflow obstruction ( 22837378) Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728) Anxiety in major depressive disorder ( 24047446) Asthma (childhood onset) ( 31036433) Atrial fibrillation ( 30061737 29892015) Attention deficit hyperactivity disorder ( 18839057) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 29059683) Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216) Crohn's disease ( 23128233) Diabetic retinopathy ( 21441570) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Eosinophil percentage of granulocytes ( 27863252) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hand grip strength ( 29691431) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 29403010 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Pre-treatment viral load in HIV-1 infection ( 31219150) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Smoking behaviour (cigarettes smoked per day) ( 31217584) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) White blood cell count ( 29403010 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		40 interacting genes: ADAMTSL4 ATF2 COL8A1 EFEMP2 FOS FOSL1 FOSL2 JUN KIFC3 KRT15 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LGALS13 MDFI MGAT5B MTUS2 NOTCH2NLA RBPMS RGS20 RIMBP3 SPOP SPRY1 SPRY2 TRAF2 TRIM23 TRIP6 TSGA10	29 interacting genes: ADAMTSL4 CATSPER1 CREB5 DHX57 DOCK2 FBXW5 HOXA1 KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE3C LCE3E LCE4A MAPKBP1 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PRKAB2 REL SMCP SPRY2 YIPF3
Entrez ID		9586	85280
HPRD ID		09896	13951
Ensembl ID		ENSG00000146592	ENSG00000241595
Uniprot IDs		Q02930	Q9BYQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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