MACF1 and TANGO6

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		MACF1	TANGO6
Description		microtubule actin crosslinking factor 1	transport and golgi organization 6 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytoskeleton Microtubule Intermediate Filament Plasma Membrane Actin Cytoskeleton Membrane Ruffle Membrane	Integral Component Of Membrane
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding ATPase Activity Cadherin Binding Microtubule Minus-end Binding Actin Filament Binding
	Biological Process	Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Regulation Of Cell Migration Regulation Of Microtubule-based Process Wound Healing Golgi To Plasma Membrane Protein Transport Intermediate Filament Cytoskeleton Organization Positive Regulation Of Axon Extension Regulation Of Focal Adhesion Assembly Regulation Of Neuron Projection Arborization	Protein Secretion
Pathways
Drugs
Diseases
GWAS		Beard thickness ( 26926045) Body mass index ( 29273807) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Colorectal cancer ( 27207650) Glucagon levels in response to oral glucose tolerance test (fasting) ( 29093273) HDL cholesterol ( 25961943 20686565) Headache ( 29397368) Heel bone mineral density ( 30598549) Loneliness (multivariate analysis) ( 27629369) Mean corpuscular hemoglobin concentration ( 27863252) Optic disc size ( 31809533) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Type 2 diabetes ( 27189021 30054458 29358691 30297969 29632382 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382)	Body mass index ( 26426971) Primary sclerosing cholangitis ( 27992413)
Interacting Genes		27 interacting genes: ACTA1 APC ATF7IP CDC5L CEP63 CNTNAP2 CNTNAP4 DISC1 DTNBP1 ESRRA EXOC1 GOLGA4 JUN MAPK9 MAPRE1 MTNR1B NRCAM NRXN1 NRXN2 PLXND1 PRKCD SKIL SRPK2 TANGO6 TNIK TRAF3IP1 UBC	2 interacting genes: MACF1 MTNR1B
Entrez ID		23499	79613
HPRD ID		09750	13353
Ensembl ID		ENSG00000127603	ENSG00000103047
Uniprot IDs		Q6ZSD7 Q9UPN3	B3KTB6 Q9C0B7
PDB IDs		4Z6G 5VE9 5X57
Enriched GO Terms of Interacting Partners?
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