FLNA and SVIL

  • Number of citations of the paper that reports this interaction (PubMedID 26496610)
  • 285
  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid)

FLNA

SVIL

Description filamin A supervillin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Bone fracture in osteoporosis ( 28580392)
  • Estimated glomerular filtration rate ( 31152163)
  • Lung function (FEV1/FVC) ( 28166213)
  • Metabolite levels ( 23823483)
  • Neurofibrillary tangles ( 25188341)
  • Normalized brain volume ( 19010793)
  • Platelet thrombus formation ( 22550155)
Interacting Genes 87 interacting genes: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA1 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DRD1 DRD2 DRD3 ERBB3 F3 FABP1 FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HNRNPD ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MCPH1 MTDH MTNR1A MTNR1B MYOT NLGN3 NPHP1 OPRM1 PAK1 PCBP2 PRKCA PSEN1 PSEN2 RAC1 RALA REL RFLNA RHOA SELE SH2B3 SHBG SIGLEC10 SIRPA SMAD3 SMAD5 SRC SVIL SYNPO2 TCF4 TLR10 TNIP2 TP73 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG 36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID 2316 6840
HPRD ID 02060 04992
Ensembl ID ENSG00000196924 ENSG00000197321
Uniprot IDs P21333 Q60FE5 Q6NXF2 O95425 Q569J5
PDB IDs 2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2MTP 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH 4M9P 4P3W 5XR1 6D8C 6EW1 2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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