PDS5B and PALB2

Number of citations of the paper that reports this interaction (PubMedID 27924011)
11

Data Source:
BioGRID (pull down)

		PDS5B	PALB2
Description		PDS5 cohesin associated factor B	partner and localizer of BRCA2
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol	Nucleoplasm
	Molecular Function	DNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Lens Development In Camera-type Eye DNA Repair Mitotic Sister Chromatid Cohesion Cell Proliferation Negative Regulation Of Cell Proliferation Regulation Of Cell Proliferation Cell Division Neuroblast Migration	Double-strand Break Repair Via Homologous Recombination Somitogenesis Inner Cell Mass Cell Proliferation Mesoderm Development Animal Organ Morphogenesis Multicellular Organism Growth Post-anal Tail Morphogenesis Negative Regulation Of Apoptotic Process Embryonic Organ Development
Pathways		Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion	HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases			Fanconi anemia
GWAS		Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309) Asthma ( 27611488) Body mass index ( 25673413) Circulating fibroblast growth factor 23 levels ( 30217807) Coronary artery disease ( 29212778) Logical memory (delayed recall) ( 29274321) Lung cancer ( 28604730) Mean platelet volume ( 27863252) Squamous cell lung carcinoma ( 28604730) Total ventricular volume (Alzheimer's disease interaction) ( 21116278)	Bipolar disorder ( 17554300)
Interacting Genes		5 interacting genes: APP BRCA2 HASPIN PALB2 RAD51	28 interacting genes: BCAS3 BRCA2 CASZ1 CCL5 CST6 DIRAS3 ERRFI1 GREB1 HNRNPC IL13RA2 IL24 KLK6 LRATD2 LYPD3 MRC2 NAT2 PDS5B PRDM14 RAD51 RAD51AP1 RAD51C RHOBTB2 RNF168 SERPINB5 SNAI1 THRSP USP2 XRCC3
Entrez ID		23047	79728
HPRD ID		05624	07966
Ensembl ID		ENSG00000083642	ENSG00000083093
Uniprot IDs		Q9NTI5	H3BN63 Q86YC2
PDB IDs		5HDT	2W18 3EU7
Enriched GO Terms of Interacting Partners?
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