PALB2 and RAD51AP1

Number of citations of the paper that reports this interaction (PubMedID 20871616)
65

Data Source:
BioGRID (pull down)

		PALB2	RAD51AP1
Description		partner and localizer of BRCA2	RAD51 associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	DNA Binding Protein Binding	Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Somitogenesis Inner Cell Mass Cell Proliferation Mesoderm Development Animal Organ Morphogenesis Multicellular Organism Growth Post-anal Tail Morphogenesis Negative Regulation Of Apoptotic Process Embryonic Organ Development	Double-strand Break Repair Via Homologous Recombination DNA Repair Regulation Of Double-strand Break Repair Via Homologous Recombination Interstrand Cross-link Repair Cellular Response To Ionizing Radiation
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange	HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases		Fanconi anemia
GWAS		Bipolar disorder ( 17554300)	Colorectal cancer ( 23263487) Phosphorus levels ( 20558539)
Interacting Genes		28 interacting genes: BCAS3 BRCA2 CASZ1 CCL5 CST6 DIRAS3 ERRFI1 GREB1 HNRNPC IL13RA2 IL24 KLK6 LRATD2 LYPD3 MRC2 NAT2 PDS5B PRDM14 RAD51 RAD51AP1 RAD51C RHOBTB2 RNF168 SERPINB5 SNAI1 THRSP USP2 XRCC3	8 interacting genes: APP DMC1 LRRK2 MAP3K1 NEDD4 PALB2 RAD51 SIAH1
Entrez ID		79728	10635
HPRD ID		07966	04350
Ensembl ID		ENSG00000083093	ENSG00000111247
Uniprot IDs		H3BN63 Q86YC2	Q96B01
PDB IDs		2W18 3EU7
Enriched GO Terms of Interacting Partners?
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