PALB2 and DIRAS3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		PALB2	DIRAS3
Description		partner and localizer of BRCA2	DIRAS family GTPase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Plasma Membrane
	Molecular Function	DNA Binding Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Somitogenesis Inner Cell Mass Cell Proliferation Mesoderm Development Animal Organ Morphogenesis Multicellular Organism Growth Post-anal Tail Morphogenesis Negative Regulation Of Apoptotic Process Embryonic Organ Development	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression By Genetic Imprinting Small GTPase Mediated Signal Transduction
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases		Fanconi anemia
GWAS		Bipolar disorder ( 17554300)
Interacting Genes		28 interacting genes: BCAS3 BRCA2 CASZ1 CCL5 CST6 DIRAS3 ERRFI1 GREB1 HNRNPC IL13RA2 IL24 KLK6 LRATD2 LYPD3 MRC2 NAT2 PDS5B PRDM14 RAD51 RAD51AP1 RAD51C RHOBTB2 RNF168 SERPINB5 SNAI1 THRSP USP2 XRCC3	12 interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 KRAS PALB2 PPM1D PTPN1 TGFB1 WT1
Entrez ID		79728	9077
HPRD ID		07966	05547
Ensembl ID		ENSG00000083093	ENSG00000162595
Uniprot IDs		H3BN63 Q86YC2	O95661
PDB IDs		2W18 3EU7
Enriched GO Terms of Interacting Partners?
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