FAM161A and IKZF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FAM161A	IKZF1
Description		FAM161 centrosomal protein A	IKAROS family zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Astral Microtubule Photoreceptor Inner Segment Centrosome Spindle Microtubule Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole	Nucleus Nucleoplasm Cytoplasm Nuclear Pericentric Heterochromatin Protein-containing Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Visual Perception Cilium Organization Response To Stimulus Cilium Assembly Positive Regulation Of Protein Acetylation	Chromatin Organization Cell Cycle Mesoderm Development Lymphocyte Differentiation Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Atrial fibrillation ( 29892015) Erectile dysfunction ( 30583798) Systemic lupus erythematosus ( 28714469)	Acute lymphoblastic leukemia (B-cell precursor) ( 29296818 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612 22076464 25310577 23512250 19684603 19684604) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299 29296818) Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever or eczema) ( 29083406) Area under the curve of insulin levels ( 24699409) Aspartate aminotransferase levels ( 29403010) B cell acute lymphoblastic leukaemia (hyperdiploid negative) ( 29296818) B cell acute lymphoblastic leukaemia (normal cytogenetics) ( 29296818) B cell acute lymphoblastic leukaemia (Philadelphia chromosome negative) ( 29296818) B-cell acute lymphoblastic leukaemia ( 31767839) Bitter taste perception (phenylthiocarbamide) in obesity with metabolic syndrome ( 31005965) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe mucosal involvement ( 25672763) Crohn's disease ( 21102463) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Glucose homeostasis traits ( 25524916) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 28552196) Hemoglobin levels ( 28017375) High density lipoprotein cholesterol levels ( 29403010) Hippocampal atrophy ( 19668339) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 29403010 28453575 27863252 28017375 19862010) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Mosquito bite size ( 28199695) Multiple sclerosis ( 24076602) N-glycan levels ( 31163085) Neutrophil percentage of white cells ( 27863252) Non-albumin protein levels ( 29403010) Red blood cell count ( 29403010 27863252) Red blood cell traits ( 23222517) Serum total protein level ( 29403010) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 23273568 26663301 26502338 28714469 19838193 19838195) Tonsillectomy ( 27182965 28928442) Total cholesterol levels ( 29403010) Type 1 diabetes ( 25751624)
Interacting Genes		66 interacting genes: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC33 CCDC57 CCNDBP1 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 DVL2 EHMT2 FAM9B FSD2 GOLGA2 HMBOX1 IKZF1 KASH5 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LMNA LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 PPFIA1 PPM1F RINT1 RUNDC3A SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A	79 interacting genes: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 DCX DDB1 DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FOXP1 FRMD6 GLRX3 GMCL2 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LHX4 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MPPED2 NEK6 NME7 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RNF6 RUNX1 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SHFL SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I ZMAT2 ZNF417 ZNF581
Entrez ID		84140	10320
HPRD ID		18996	04318
Ensembl ID		ENSG00000170264	ENSG00000185811
Uniprot IDs		Q3B820	A0A2R8Y4D3 C9JTB0 Q13422 R9R4D9
PDB IDs			6H0F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?