TRAK1 and OGT

Number of citations of the paper that reports this interaction (PubMedID 12724313)
80

Data Source:
HPRD (in vivo, in vitro)

		TRAK1	OGT
Description		trafficking kinesin protein 1	O-linked N-acetylglucosamine (GlcNAc) transferase
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Mitochondrion Early Endosome Cell Cortex Dendrite Cytoplasmic Vesicle Mitochondrial Membrane Axonal Growth Cone Perinuclear Region Of Cytoplasm Axon Cytoplasm	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Mitochondrial Membrane Protein-containing Complex Cell Projection
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding TPR Domain Binding GABA Receptor Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific) Protein O-GlcNAc Transferase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Anterograde Axonal Transport Protein Localization Endosome To Lysosome Transport Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Dendrite Morphogenesis Positive Regulation Of Axonogenesis Anterograde Axonal Transport Of Mitochondrion	Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Viral Process Protein Processing Protein Deubiquitination Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K27 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Cold-induced Thermogenesis
Pathways		Signaling by BRAF and RAF fusions	HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS		Body mass index ( 28552196) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		7 interacting genes: CDC5L CDK6 HGS OGT POLR2A SKIL TRAF3IP1	22 interacting genes: CSNK2A1 CSNK2B GSK3B HCFC1 HIRA MAPT MTDH NUP62 NUP62CL OGA PHC3 PSG1 SIN3A SNAP91 SP1 SRF TAB1 TAB3 TRAK1 TRAK2 UBC YES1
Entrez ID		22906	8473
HPRD ID		09732	02222
Ensembl ID		ENSG00000182606	ENSG00000147162
Uniprot IDs		A0A087X0N0 B7Z218 B7ZAE5 Q9UPV9	O15294
PDB IDs			1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4CDR 4GYW 4GYY 4GZ3 4GZ5 4GZ6 4N39 4N3A 4N3B 4N3C 4XI9 4XIF 5BNW 5C1D 5HGV 5LVV 5LWV 5NPR 5NPS 5VIE 5VIF 6E37 6EOU 6IBO 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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