VPS41 and AKTIP

Number of citations of the paper that reports this interaction (PubMedID 18799622)
41

Data Source:
HPRD (in vivo)

		VPS41	AKTIP
Description		VPS41 subunit of HOPS complex	AKT interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex	Cytosol Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Targeting To Vacuole Autophagy Endosome To Lysosome Transport Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Vacuole Fusion, Non-autophagic Regulated Exocytosis Late Endosome To Lysosome Transport	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 25673412) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	26 interacting genes: AKT1 ASS1 CEP126 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MARCHF5 MATR3 PDPK1 POLA2 RPA1 TRIM23 TRIM41 TWNK UTP14A VPS16 VPS18 VPS41
Entrez ID		27072	64400
HPRD ID		10402	07467
Ensembl ID		ENSG00000006715	ENSG00000166971
Uniprot IDs		P49754	A0A024R6S6 A0A024R6T5 Q9H8T0
PDB IDs
Enriched GO Terms of Interacting Partners?
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