EVPL and KRT1

Number of citations of the paper that reports this interaction (PubMedID 8999895)
28

Data Source:
HPRD (in vivo)

		EVPL	KRT1
Description		envoplakin	keratin 1
Image
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding	Protein Binding Carbohydrate Binding Structural Constituent Of Epidermis Signaling Receptor Activity Protein Heterodimerization Activity
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Keratinization Fibrinolysis Neutrophil Degranulation Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier Cornification
Pathways		Formation of the cornified envelope	Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs			Zinc Copper
Diseases			Epidermolytic palmoplantar keratoderma (EPPK) Ichthyosis hystrix, Curth-Macklin type Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE) Striate palmoplantar keratoderma
GWAS		Depressive symptom improvement ( 30468137) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	21 interacting genes: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT15 KRT33B KRT5 LINC00839 LORICRIN MBL2 NINL PDE4DIP PI3 PRKCE UBE3A YWHAQ
Entrez ID		2125	3848
HPRD ID		03352	00763
Ensembl ID		ENSG00000167880	ENSG00000167768
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	P04264
PDB IDs		4QMD	4ZRY 6E2J 6UUI
Enriched GO Terms of Interacting Partners?
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