EVPL and KRT10

Number of citations of the paper that reports this interaction (PubMedID 8999895)
28

Data Source:
HPRD (in vivo)

		EVPL	KRT10
Description		envoplakin	keratin 10
Image
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome	Cornified Envelope Extracellular Space Nucleus Cytoplasm Cytosol Intermediate Filament Cell Surface Membrane Extracellular Exosome
	Molecular Function	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding	Protein Binding Structural Constituent Of Epidermis Protein Heterodimerization Activity
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Peptide Cross-linking Keratinocyte Differentiation Keratinization Positive Regulation Of Epidermis Development Protein Heterotetramerization Cornification
Pathways		Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Zinc Copper
Diseases			Ichthyosis with confetti; Congenital reticular ichthyosiform erythroderma; Ichthyosis variegata Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
GWAS		Depressive symptom improvement ( 30468137) Metabolite levels ( 23823483)	Glucose homeostasis traits ( 25524916)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	7 interacting genes: AKT1 ESR1 EVPL GLE1 PRKCZ SIRPA SMAD3
Entrez ID		2125	3858
HPRD ID		03352	01021
Ensembl ID		ENSG00000167880	ENSG00000186395
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	P13645
PDB IDs		4QMD	3ASW 4F1Z 4ZRY 6E2J 6EC0 6UUI
Enriched GO Terms of Interacting Partners?
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