KRT1 and IVL

Number of citations of the paper that reports this interaction (PubMedID 8999895)
28

Data Source:
BioGRID (pull down)

		KRT1	IVL
Description		keratin 1	involucrin
Image
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Structural Constituent Of Epidermis Signaling Receptor Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Keratinization Fibrinolysis Neutrophil Degranulation Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier Cornification	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Cornification
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Formation of the cornified envelope
Drugs		Zinc Copper
Diseases		Epidermolytic palmoplantar keratoderma (EPPK) Ichthyosis hystrix, Curth-Macklin type Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE) Striate palmoplantar keratoderma
GWAS			Asthma ( 31619474) Vitamin D levels ( 26704534)
Interacting Genes		21 interacting genes: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT15 KRT33B KRT5 LINC00839 LORICRIN MBL2 NINL PDE4DIP PI3 PRKCE UBE3A YWHAQ	9 interacting genes: ACD CSTA DSP EVPL KRT1 LORICRIN POT1 SPRR3 UCHL5
Entrez ID		3848	3713
HPRD ID		00763	00931
Ensembl ID		ENSG00000167768	ENSG00000163207
Uniprot IDs		P04264	P07476
PDB IDs		4ZRY 6E2J 6UUI	1EU0
Enriched GO Terms of Interacting Partners?
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