EMD and CATSPER1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		EMD	CATSPER1
Description		emerin	cation channel sperm associated 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Microtubule Membrane Integral Component Of Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum	Plasma Membrane Motile Cilium CatSper Complex
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding
	Biological Process	Muscle Contraction Mitotic Nuclear Envelope Reassembly Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway	Calcium Ion Transport Multicellular Organism Development Spermatogenesis Cell Differentiation Flagellated Sperm Motility Response To Progesterone Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Transmembrane Transport
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Sperm Motility And Taxes
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340)
Interacting Genes		45 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CEP70 COPS6 CREB3 CTNNBIP1 DPPA4 EFHC2 FATE1 GMCL1 KASH5 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX2 MTNR1A PAK5 PSME1 RNF123 SH3GL2 SH3GL3 SRC STX4 SYNE1 TRAF3IP3 TRIM42 VAPB VAV1 YTHDC1 ZFP64 ZNF165 ZNF232	33 interacting genes: ADAMTSL4 AGR2 APOA2 BEGAIN CHIC2 CHRD EFEMP2 EMD KHDRBS2 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MTUS2 NOTCH2NLA PLSCR1 PLSCR3 RFX6 RGS20 RIMBP3 SCRG1 SPRY2 TRAF2 TRIP6
Entrez ID		2010	117144
HPRD ID		02309	09396
Ensembl ID		ENSG00000102119	ENSG00000175294
Uniprot IDs		P50402	Q8NEC5
PDB IDs		1JEI 2ODC 2ODG 6GHD
Enriched GO Terms of Interacting Partners?
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