EMD and LMO7

Number of citations of the paper that reports this interaction (PubMedID 17620012)
68

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		EMD	LMO7
Description		emerin	LIM domain 7
Image
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Microtubule Membrane Integral Component Of Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum	Ubiquitin Ligase Complex Nucleus Nuclear Envelope Cytoplasm Cytosol Focal Adhesion Cell Surface Apical Plasma Membrane
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	Ubiquitin-protein Transferase Activity Metal Ion Binding
	Biological Process	Muscle Contraction Mitotic Nuclear Envelope Reassembly Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway	Protein Polyubiquitination Protein Ubiquitination Regulation Of Signaling Regulation Of Cell Adhesion Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS			Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29449654) Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Intraocular pressure ( 29617998 29785010 31959993 30054594) Multiple system atrophy (pathologically confirmed) ( 27629089) Obsessive-compulsive disorder ( 30456828) Type 1 diabetes ( 21980299)
Interacting Genes		45 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CEP70 COPS6 CREB3 CTNNBIP1 DPPA4 EFHC2 FATE1 GMCL1 KASH5 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX2 MTNR1A PAK5 PSME1 RNF123 SH3GL2 SH3GL3 SRC STX4 SYNE1 TRAF3IP3 TRIM42 VAPB VAV1 YTHDC1 ZFP64 ZNF165 ZNF232	10 interacting genes: ABCA1 CALM1 EMD MDM2 PKM RHOU SRPK2 UBAC2 YWHAG YWHAQ
Entrez ID		2010	4008
HPRD ID		02309	05078
Ensembl ID		ENSG00000102119	ENSG00000136153
Uniprot IDs		P50402	A0A0A0MTE2 E9PMT2 F8J2B5 F8WD26 Q8WWI1
PDB IDs		1JEI 2ODC 2ODG 6GHD	2EAQ
Enriched GO Terms of Interacting Partners?
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