CATSPER1 and CHRD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CATSPER1	CHRD
Description		cation channel sperm associated 1	chordin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Motile Cilium CatSper Complex	Extracellular Space
	Molecular Function	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding	Protein Binding Heparin Binding Cytokine Binding Syndecan Binding
	Biological Process	Calcium Ion Transport Multicellular Organism Development Spermatogenesis Cell Differentiation Flagellated Sperm Motility Response To Progesterone Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Transmembrane Transport	Skeletal System Development Osteoblast Differentiation Gastrulation With Mouth Forming Second Mesoderm Formation Positive Regulation Of Mesenchymal Cell Proliferation BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Negative Regulation Of Cell Migration Negative Regulation Of BMP Signaling Pathway Forebrain Development Floor Plate Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Cell Adhesion
Pathways		Sperm Motility And Taxes
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340)	Diisocyanate-induced asthma ( 25918132) Platelet count ( 20139978) Plateletcrit ( 27863252)
Interacting Genes		33 interacting genes: ADAMTSL4 AGR2 APOA2 BEGAIN CHIC2 CHRD EFEMP2 EMD KHDRBS2 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MTUS2 NOTCH2NLA PLSCR1 PLSCR3 RFX6 RGS20 RIMBP3 SCRG1 SPRY2 TRAF2 TRIP6	26 interacting genes: ATN1 BMP1 BMP2 CATSPER1 CD36 F2R HOXA1 HRG KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 KRTAP9-2 MEOX2 NOTCH2NLA NR0B2 OTX1 PLSCR1 SMAD3 SPRY2 TLL1 TWSG1
Entrez ID		117144	8646
HPRD ID		09396	04592
Ensembl ID		ENSG00000175294	ENSG00000090539
Uniprot IDs		Q8NEC5	E7ESX1 Q8N2W7 Q9H2X0
PDB IDs
Enriched GO Terms of Interacting Partners?
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