EIF5 and EIF1AY

Number of citations of the paper that reports this interaction (PubMedID 12569173)
30

		EIF5	EIF1AY
Description		eukaryotic translation initiation factor 5	eukaryotic translation initiation factor 1A Y-linked
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	RNA Binding Translation Initiation Factor Activity GTPase Activity GDP-dissociation Inhibitor Activity Protein Binding GTP Binding Translation Factor Activity, RNA Binding Cadherin Binding Eukaryotic Initiation Factor EIF2 Binding	Translation Initiation Factor Activity Protein Binding
	Biological Process	Formation Of Translation Preinitiation Complex Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation Activation Of GTPase Activity	Translational Initiation
Pathways		Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Monocyte count ( 29403010) Number of sexual partners ( 30643258) Red blood cell traits ( 23222517)
Interacting Genes		15 interacting genes: APP CSNK2A1 CSNK2B DUSP12 EIF1AX EIF1AY EIF2S2 EIF3D EIF3G EIF4G1 EIF4G2 HSPB1 NCBP2 NRGN PUM1	4 interacting genes: ATXN1 EIF5 HNF4A SRPK2
Entrez ID		1983	9086
HPRD ID		03417	02455
Ensembl ID		ENSG00000100664	ENSG00000198692
Uniprot IDs		A0A024R6Q1 P55010	A6NJH9 O14602
PDB IDs		2E9H 2G2K 2IU1
Enriched GO Terms of Interacting Partners?
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