DPYSL3 and DPYSL5

Number of citations of the paper that reports this interaction (PubMedID 10956643)
46

Data Source:
HPRD (in vivo)

		DPYSL3	DPYSL5
Description		dihydropyrimidinase like 3	dihydropyrimidinase like 5
Image
GO Annotations	Cellular Component	Extracellular Space Cytosol Lamellipodium Growth Cone Filamentous Actin Cell Body Synapse Exocytic Vesicle	Cytosol Dendrite Neuronal Cell Body
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides SH3 Domain Binding Filamin Binding Chondroitin Sulfate Binding Identical Protein Binding	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides
	Biological Process	Pyrimidine Nucleobase Catabolic Process Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Migration Neuron Development Response To Axon Injury Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Actin Crosslink Formation Cellular Response To Cytokine Stimulus	Pyrimidine Nucleobase Catabolic Process Signal Transduction Nervous System Development Axon Guidance
Pathways		CRMPs in Sema3A signaling	CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Excessive daytime sleepiness ( 27992416) Metabolite levels ( 23823483)	Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Obesity-related traits ( 23251661) Reflection (response to stress) ( 30886212) Urate levels ( 31578528) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		7 interacting genes: ACD DISC1 DPYSL5 HYOU1 POT1 TERF1 TNIK	9 interacting genes: APPL1 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FBN2 FES HSPA5
Entrez ID		1809	56896
HPRD ID		03104	10522
Ensembl ID		ENSG00000113657	ENSG00000157851
Uniprot IDs		A0A140VK07 Q14195 Q6DEN2 Q8IXW6	Q9BPU6
PDB IDs		4BKN 4CNS 4CNT 4CNU	4B90 4B91 4B92
Enriched GO Terms of Interacting Partners?
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