DPYSL5 and DPYSL2

Number of citations of the paper that reports this interaction (PubMedID 10956643)
46

Data Source:
HPRD (in vivo)

		DPYSL5	DPYSL2
Description		dihydropyrimidinase like 5	dihydropyrimidinase like 2
Image
GO Annotations	Cellular Component	Cytosol Dendrite Neuronal Cell Body	Cytosol Microtubule Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Identical Protein Binding
	Biological Process	Pyrimidine Nucleobase Catabolic Process Signal Transduction Nervous System Development Axon Guidance	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Endocytosis Cytoskeleton Organization Signal Transduction Nervous System Development Axon Guidance Brain Development Regulation Of Axon Extension
Pathways		CRMPs in Sema3A signaling	CRMPs in Sema3A signaling Recycling pathway of L1
Drugs			Artenimol
Diseases
GWAS		Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Obesity-related traits ( 23251661) Reflection (response to stress) ( 30886212) Urate levels ( 31578528) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Bitter alcoholic beverage consumption ( 31046077) Diastolic blood pressure ( 30224653) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		9 interacting genes: APPL1 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FBN2 FES HSPA5	14 interacting genes: AP2A1 CRMP1 DISC1 DPYSL4 DPYSL5 GORASP2 GSK3B LEF1 NUMB PLD2 ROCK1 TNIK TUBB UBE2I
Entrez ID		56896	1808
HPRD ID		10522	03914
Ensembl ID		ENSG00000157851	ENSG00000092964
Uniprot IDs		Q9BPU6	A0A1C7CYX9 Q16555 Q59GB4
PDB IDs		4B90 4B91 4B92	2GSE 2VM8 5LXX 5MKV 5MLE 5X1A 5X1C 5X1D 5YZ5 5YZA 5YZB 6JV9 6JVB
Enriched GO Terms of Interacting Partners?
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