DMPK and PVR

		DMPK	PVR
Description		DM1 protein kinase	PVR cell adhesion molecule
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GO Annotations	Cellular Component	Cell Nuclear Outer Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Mitochondrial Outer Membrane Nuclear Membrane Sarcoplasmic Reticulum Membrane	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Myosin Phosphatase Regulator Activity Metal Ion Binding	Virus Receptor Activity Protein Binding Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Regulation Of Sodium Ion Transport Protein Phosphorylation Cellular Calcium Ion Homeostasis Nuclear Envelope Organization Regulation Of Heart Contraction Muscle Cell Apoptotic Process Regulation Of Myotube Differentiation Regulation Of Skeletal Muscle Contraction By Calcium Ion Signaling Regulation Of Excitatory Postsynaptic Membrane Potential Involved In Skeletal Muscle Contraction Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Synapse Structural Plasticity Regulation Of Cardiac Conduction	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Ion homeostasis	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization
Drugs		3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione	Sphingosine Myristic acid
Diseases		Myotonic dystrophy (DM)
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143)	Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376)
Interacting Genes		19 interacting genes: ANXA7 ATN1 ATXN1 CELF1 FXYD1 GABARAP GEMIN4 HOXA2 HSPB2 PIN1 PLN PPP1R12A PVR RAC1 RAF1 RPS10 SMN1 TK1 UBQLN4	25 interacting genes: AP1M2 CD226 CD96 DMPK DYNLT1 DYNLT3 GMEB2 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NECTIN1 NECTIN2 NECTIN3 NOTCH2NLA PLA2G3 PLAT PSG11 PSG9 PSMD8 SLC22A4 SLC30A2 TIGIT VTN WNK1
Entrez ID		1760	5817
HPRD ID		05645	01434
Ensembl ID		ENSG00000104936	ENSG00000073008
Uniprot IDs		B4DM55 B4DZE2 E5KR05 E5KR06 E5KR07 I6L989 Q09013	A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151
PDB IDs		1WT6 2VD5	1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?
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