PVR and SLC30A2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PVR	SLC30A2
Description		PVR cell adhesion molecule	solute carrier family 30 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Virus Receptor Activity Protein Binding Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization	Zinc efflux and compartmentalization by the SLC30 family
Drugs		Sphingosine Myristic acid
Diseases
GWAS		Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376)
Interacting Genes		25 interacting genes: AP1M2 CD226 CD96 DMPK DYNLT1 DYNLT3 GMEB2 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NECTIN1 NECTIN2 NECTIN3 NOTCH2NLA PLA2G3 PLAT PSG11 PSG9 PSMD8 SLC22A4 SLC30A2 TIGIT VTN WNK1	11 interacting genes: ADAM33 CCL4 CCL4L2 CD99L2 CREB3 KASH5 LMNA LTA PVR SERPING1 TNFRSF12A
Entrez ID		5817	7780
HPRD ID		01434	18057
Ensembl ID		ENSG00000073008	ENSG00000158014
Uniprot IDs		A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151	Q9BRI3
PDB IDs		1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?
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