DFFB and DFFA

Number of citations of the paper that reports this interaction (PubMedID 9422506)
468

Data Source:
HPRD (in vivo, in vitro)

		DFFB	DFFA
Description		DNA fragmentation factor subunit beta	DNA fragmentation factor subunit alpha
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Protein-containing Complex	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Deoxyribonuclease Activity Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Disordered Domain Specific Binding	Protein Binding Protein Domain Specific Binding Protein Binding Involved In Protein Folding Deoxyribonuclease Inhibitor Activity
	Biological Process	DNA Catabolic Process Apoptotic DNA Fragmentation Apoptotic Chromosome Condensation	Apoptotic DNA Fragmentation Negative Regulation Of Deoxyribonuclease Activity Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Chaperone-mediated Protein Folding Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Apoptotic DNA Fragmentation
Pathways		Apoptosis induced DNA fragmentation	Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494) Metabolite levels ( 23823483)	Depression in smokers ( 30219690) Male-pattern baldness ( 29146897 28196072)
Interacting Genes		4 interacting genes: APP CIDEB DFFA TOP2A	11 interacting genes: CASP3 CASP7 CIDEB DFFB EWSR1 GZMB GZMM NECAB2 STRN4 YWHAG YWHAZ
Entrez ID		1677	1676
HPRD ID		03532	03531
Ensembl ID		ENSG00000169598	ENSG00000160049
Uniprot IDs		B4DZS0 O76075 Q96P72 Q96P73 Q96P74	A0A024R4H5 O00273
PDB IDs		1IBX	1IBX 1IYR 1KOY
Enriched GO Terms of Interacting Partners?
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