DFFA and GZMM

Number of citations of the paper that reports this interaction (PubMedID 16818775)
12

Data Source:
BioGRID (enzymatic study)

		DFFA	GZMM
Description		DNA fragmentation factor subunit alpha	granzyme M
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane Protein-containing Complex	Extracellular Region Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein Binding Involved In Protein Folding Deoxyribonuclease Inhibitor Activity	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	Apoptotic DNA Fragmentation Negative Regulation Of Deoxyribonuclease Activity Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Chaperone-mediated Protein Folding Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Apoptotic DNA Fragmentation	T Cell Mediated Cytotoxicity Proteolysis Apoptotic Process Cell Death Cytolysis Innate Immune Response
Pathways		Apoptosis induced DNA fragmentation	Alternative complement activation
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Male-pattern baldness ( 29146897 28196072)	Blood protein levels ( 29875488)
Interacting Genes		11 interacting genes: CASP3 CASP7 CIDEB DFFB EWSR1 GZMB GZMM NECAB2 STRN4 YWHAG YWHAZ	5 interacting genes: DFFA EZR NPM1 PARP1 TUBA1B
Entrez ID		1676	3004
HPRD ID		03531	02633
Ensembl ID		ENSG00000160049	ENSG00000197540
Uniprot IDs		A0A024R4H5 O00273	P51124
PDB IDs		1IBX 1IYR 1KOY	1LZP 2ZGC 2ZGH 2ZGJ 2ZKS
Enriched GO Terms of Interacting Partners?
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