ADRB2 and GRK6

  • Number of citations of the paper that reports this interaction (PubMedID 9819198)
  • 16
  • Data Source:
  • HPRD (in vitro)

ADRB2

GRK6

Description adrenoceptor beta 2 G protein-coupled receptor kinase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Activated partial thromboplastin time ( 22703881)
  • Blood protein levels ( 28240269)
  • Cardiac troponin-I levels ( 31014085)
  • Chronic kidney disease ( 20383146)
  • Extremely high intelligence ( 29520040)
  • Glycine levels ( 30837465)
  • Intelligence (MTAG) ( 29326435)
  • Metabolite levels ( 22916037)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 92 interacting genes: ADGRG1 ADRB3 AKAP12 AKAP5 ALDOA ARF4 ARHGAP5 ARHGDIA ARR3 ARRB1 ARRB2 ARRDC3 CCKBR CD4 CD68 CD81 CD9 CEACAM1 CNN1 CSK EGLN3 EIF2B1 GMPR2 GNA11 GNA14 GNA15 GNAI2 GNAS GNAT2 GNB1 GNG2 GNL3L GPR37 GPRASP1 GPRC5B GRB2 GRIA3 GRK1 GRK2 GRK3 GRK4 GRK5 GRK6 HDAC6 HTR4 IL1B IL6R INSR KCNE1 KCNJ6 KCNJ9 KCTD13 MAPK8IP2 MCAM MDM2 NEDD4 NOS1 OPRD1 PLA2G2D PRKCD PTGER1 RAB27A RAB3A RACK1 RAN RAP2C REL RGS10 RGS11 RGS17 RGS2 RGS20 RGS5 RGS8 RGS9 RHOD RNF41 SLC52A2 SLC9A3R1 SLC9A3R2 SNCG SRC STAT3 STAT4 TSG101 TSHR UCHL1 VAPA VDAC1 VDAC2 VEGFB WNK1 19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R
Entrez ID 154 2870
HPRD ID 00187 02925
Ensembl ID ENSG00000169252 ENSG00000198055
Uniprot IDs P07550 B3KPS5 P43250
PDB IDs 1GQ4 2R4R 2R4S 2RH1 3D4S 3KJ6 3NY8 3NY9 3NYA 3P0G 3PDS 3SN6 4GBR 4LDE 4LDL 4LDO 4QKX 5D5A 5D5B 5D6L 5JQH 5X7D 6E67 6MXT 6N48 6NI3 6PRZ 6PS0 6PS1 6PS2 6PS3 6PS4 6PS5 6PS6 2ACX 3NYN 3NYO
Enriched GO Terms of Interacting Partners?
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