ADRB2 and IL6R

  • Number of citations of the paper that reports this interaction (PubMedID 24561123)
  • 3
  • Data Source:
  • BioGRID (protein complementation assay, affinity chromatography technology)

ADRB2

IL6R

Description adrenoceptor beta 2 interleukin 6 receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Abdominal aortic aneurysm ( 27899403)
  • Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001)
  • Albumin-globulin ratio ( 29403010)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Ankylosing spondylitis ( 23749187)
  • Asthma ( 21907864)
  • Atopic dermatitis ( 26482879)
  • Atrial fibrillation ( 29892015)
  • Blood protein levels ( 30072576 29875488 28240269 23696881)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • C-reactive protein ( 19567438 18439548)
  • C-reactive protein levels ( 29403010 30388399 21300955)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Coronary artery disease ( 29212778 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Fibrinogen ( 20031577 23969696)
  • Fibrinogen levels ( 28107422 26561523)
  • Itch intensity from mosquito bite ( 28199695)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Monocyte percentage of white cells ( 27863252)
  • Mosquito bite size ( 28199695)
  • Myocardial infarction ( 26343387)
  • Parental longevity (combined parental attained age, Martingale residuals) ( 29227965)
  • Protein quantitative trait loci ( 18464913)
  • Pulmonary function ( 17903307)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) ( 24554482)
  • Rheumatoid arthritis ( 30423114 23143596 24390342)
  • Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 92 interacting genes: ADGRG1 ADRB3 AKAP12 AKAP5 ALDOA ARF4 ARHGAP5 ARHGDIA ARR3 ARRB1 ARRB2 ARRDC3 CCKBR CD4 CD68 CD81 CD9 CEACAM1 CNN1 CSK EGLN3 EIF2B1 GMPR2 GNA11 GNA14 GNA15 GNAI2 GNAS GNAT2 GNB1 GNG2 GNL3L GPR37 GPRASP1 GPRC5B GRB2 GRIA3 GRK1 GRK2 GRK3 GRK4 GRK5 GRK6 HDAC6 HTR4 IL1B IL6R INSR KCNE1 KCNJ6 KCNJ9 KCTD13 MAPK8IP2 MCAM MDM2 NEDD4 NOS1 OPRD1 PLA2G2D PRKCD PTGER1 RAB27A RAB3A RACK1 RAN RAP2C REL RGS10 RGS11 RGS17 RGS2 RGS20 RGS5 RGS8 RGS9 RHOD RNF41 SLC52A2 SLC9A3R1 SLC9A3R2 SNCG SRC STAT3 STAT4 TSG101 TSHR UCHL1 VAPA VDAC1 VDAC2 VEGFB WNK1 10 interacting genes: ADRB2 CNTF ERAP1 IL6 IL6ST MAGI1 SRC STAT3 WWP1 WWP2
Entrez ID 154 3570
HPRD ID 00187 01000
Ensembl ID ENSG00000169252 ENSG00000160712
Uniprot IDs P07550 A0A087WTB5 A0N0L5 P08887
PDB IDs 1GQ4 2R4R 2R4S 2RH1 3D4S 3KJ6 3NY8 3NY9 3NYA 3P0G 3PDS 3SN6 4GBR 4LDE 4LDL 4LDO 4QKX 5D5A 5D5B 5D6L 5JQH 5X7D 6E67 6MXT 6N48 6NI3 6PRZ 6PS0 6PS1 6PS2 6PS3 6PS4 6PS5 6PS6 1N26 1N2Q 1P9M 2ARW 5FUC
Enriched GO Terms of Interacting Partners?
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