PLB1 and TNS2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		PLB1	TNS2
Description		phospholipase B1	tensin 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane	Cell Plasma Membrane Focal Adhesion
	Molecular Function	Phospholipase Activity Lysophospholipase Activity Phospholipase A2 Activity Retinyl-palmitate Esterase Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Protein Tyrosine Phosphatase Activity Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Retinoid Metabolic Process Phospholipid Metabolic Process Lipid Catabolic Process Phosphatidylcholine Acyl-chain Remodeling Retinol Metabolic Process Positive Regulation Of Acrosome Reaction	Kidney Development Negative Regulation Of Cell Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Intracellular Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal Homeostasis
Pathways		Acyl chain remodelling of PC Retinoid metabolism and transport
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Excessive sweating ( 29895819) Heel bone mineral density ( 30598549) Intracranial aneurysm ( 29531279) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		5 interacting genes: NLGN3 PIK3R3 RIN3 S100A1 TNS2	86 interacting genes: ADCK5 AMMECR1 AP1S2 ASB3 AXL BRCA1 C11orf87 COX6B2 CSNK1E DCAF11 DCAF8 DDIT4L DLC1 DOK3 EPB41L4A EPS8L2 ERBB2 ERBB3 FABP7 FAM114A1 FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HUWE1 ID2 IHO1 ITGB3 ITGB5 ITGB7 KIF1A KPRP KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP13-1 KRTAP23-1 KRTAP3-1 MPEG1 MT2A MTDH MYBPHL MYH7B NMU NT5C NUBP2 OBSL1 OTX1 PER1 PKP1 PLB1 PLK3 POLR3F RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SH2B3 SHFL SPATA12 SPRY2 SPRY4 SUV39H1 TBC1D16 TCP10L TEKT5 TENT5A TLE5 TM4SF19 TSC1 TWSG1 WDFY3 ZNF250 ZNF417 ZNF586 ZNF587 ZNF655 ZNF688 ZNRD1
Entrez ID		151056	23371
HPRD ID		15141	16256
Ensembl ID		ENSG00000163803	ENSG00000111077
Uniprot IDs		B2RWP8 Q6P1J6	A0A024RB48 Q63HR2
PDB IDs			2DKQ 2KNO 2L6K 2LOZ 3HQC
Enriched GO Terms of Interacting Partners?
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