CCN2 and AP3D1

Number of citations of the paper that reports this interaction (PubMedID 16457822)
43

Data Source:
HPRD (in vitro)

		CCN2	AP3D1
Description		cellular communication network factor 2	adaptor related protein complex 3 subunit delta 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cis-Golgi Network Cytosol Plasma Membrane Cell Cortex Extracellular Matrix Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix	Golgi Membrane Cell Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane AP-3 Adaptor Complex Terminal Bouton Postsynapse Presynaptic Endosome Glutamatergic Synapse Axon Cytoplasm
	Molecular Function	Fibronectin Binding Integrin Binding Protein Binding Insulin-like Growth Factor Binding Protein C-terminus Binding Growth Factor Activity Heparin Binding	Protein Binding
	Biological Process	Cartilage Condensation Ossification Angiogenesis Tissue Homeostasis Transcription Initiation From RNA Polymerase II Promoter Cell Adhesion Cell-matrix Adhesion Signal Transduction Integrin-mediated Signaling Pathway Aging Positive Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Epidermis Development Response To Wounding Response To Glucose Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Migration Cell Differentiation Lung Development Regulation Of Chondrocyte Differentiation Response To Estradiol Positive Regulation Of Collagen Biosynthetic Process Response To Anoxia Intracellular Signal Transduction Chondrocyte Proliferation Response To Amino Acid Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Peptide Hormone Positive Regulation Of Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Cell Activation Response To Mineralocorticoid Positive Regulation Of Stress Fiber Assembly Cytosolic Calcium Ion Transport Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Cell Death Extracellular Matrix Constituent Secretion Positive Regulation Of G0 To G1 Transition Positive Regulation Of ERK1 And ERK2 Cascade Response To Fatty Acid DNA Biosynthetic Process Reactive Oxygen Species Metabolic Process	Protein Targeting To Vacuole Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Melanosome Organization Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS			Height ( 28552196 31562340) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Myocardial infarction ( 24916648) Pulse pressure ( 30578418) Red blood cell count ( 27863252) Systolic blood pressure ( 30578418)
Interacting Genes		12 interacting genes: ACTB AP3D1 CCN3 ERBB4 FBLN1 HSPG2 LRP1 MTDH TGFB1 TGFB2 TGFB3 VEGFA	10 interacting genes: AP3B1 AP3S1 AP3S2 ARF1 ARF6 CCN2 RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		1490	8943
HPRD ID		00412	06260
Ensembl ID		ENSG00000118523	ENSG00000065000
Uniprot IDs		P29279 Q5M8T4	O14617
PDB IDs			4AFI
Enriched GO Terms of Interacting Partners?
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