UBE2U and MKRN3

Number of citations of the paper that reports this interaction (PubMedID 19549727)
67

Data Source:
BioGRID (two hybrid)

		UBE2U	MKRN3
Description		ubiquitin conjugating enzyme E2 U	makorin ring finger protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin HULC Complex	Ribonucleoprotein Complex
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Transferase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Severe bacterial meningitis ( 31092817)	Height ( 31562340) Menarche (age at onset) ( 25231870) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		68 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2	61 interacting genes: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 GRAP2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 NKAPD1 PEX10 PEX5 POLR1C PRPF31 PSMA1 RBM41 RBPMS RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TLE5 TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W ZNF688
Entrez ID		148581	7681
HPRD ID		14599	04836
Ensembl ID		ENSG00000177414	ENSG00000179455
Uniprot IDs		A0A140VJY9 Q5VVX9	Q13064
PDB IDs		1YRV
Enriched GO Terms of Interacting Partners?
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