UBE2U and TRIM54

Number of citations of the paper that reports this interaction (PubMedID 19690564)
57

Data Source:
BioGRID (two hybrid)

		UBE2U	TRIM54
Description		ubiquitin conjugating enzyme E2 U	tripartite motif containing 54
Image
GO Annotations	Cellular Component	Nuclear Chromatin HULC Complex	Microtubule Microtubule Associated Complex Z Disc
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Microtubule Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organism Development Cell Differentiation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Severe bacterial meningitis ( 31092817)
Interacting Genes		68 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2	132 interacting genes: ADCY4 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 C2CD6 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC87 CDK18 CDKN1A CENPX CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DEUP1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ELOA ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 HSPB1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 NTAQ1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM TBC1D22B TCEA2 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D2 UBE2D3 UBE2E3 UBE2I UBE2N UBE2U UBE2V2 UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587
Entrez ID		148581	57159
HPRD ID		14599	05928
Ensembl ID		ENSG00000177414	ENSG00000138100
Uniprot IDs		A0A140VJY9 Q5VVX9	Q9BYV2
PDB IDs		1YRV	3Q1D
Enriched GO Terms of Interacting Partners?
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