UBE2U and ZSWIM2

Number of citations of the paper that reports this interaction (PubMedID 19690564)
57

		UBE2U	ZSWIM2
Description		ubiquitin conjugating enzyme E2 U	zinc finger SWIM-type containing 2
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GO Annotations	Cellular Component	Nuclear Chromatin HULC Complex
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Zinc Ion Binding Protein Self-association Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Protein Polyubiquitination Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Severe bacterial meningitis ( 31092817)	Systolic blood pressure ( 30224653)
Interacting Genes		68 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2	2 interacting genes: MAGEA11 UBE2U
Entrez ID		148581	151112
HPRD ID		14599	15902
Ensembl ID		ENSG00000177414	ENSG00000163012
Uniprot IDs		A0A140VJY9 Q5VVX9	Q8NEG5
PDB IDs		1YRV	2DIP
Enriched GO Terms of Interacting Partners?
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