VAMP4 and PACS1

Number of citations of the paper that reports this interaction (PubMedID 14608369)
25

Data Source:
HPRD (in vivo, in vitro)

		VAMP4	PACS1
Description		vesicle associated membrane protein 4	phosphofurin acidic cluster sorting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Golgi Apparatus Plasma Membrane Cell Surface Transport Vesicle Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane	Golgi Apparatus Cytosol COPI-coated Vesicle
	Molecular Function	Protein Binding	Protein Binding Ion Channel Binding
	Biological Process	Microtubule Cytoskeleton Organization ER To Golgi Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Membrane Organization Golgi Ribbon Formation Regulation Of Synaptic Vesicle Endocytosis	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane
Pathways		Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Nef mediated downregulation of MHC class I complex cell surface expression
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Obesity (early onset extreme) ( 23563609)
Interacting Genes		11 interacting genes: AP1M1 BCL2L13 CSNK2A1 DNAJC5 KASH5 LMNA PACS1 SNAP29 STX16 STX4 STX6	10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4
Entrez ID		8674	55690
HPRD ID		06070	06320
Ensembl ID		ENSG00000117533	ENSG00000175115
Uniprot IDs		O75379 Q6IAZ3	A0A024R5H6 Q6VY07
PDB IDs
Enriched GO Terms of Interacting Partners?
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