ADRA1D and SNTA1

Number of citations of the paper that reports this interaction (PubMedID 16533813)
26

Data Source:
BioGRID (unspecified method)
HPRD (two hybrid)

		ADRA1D	SNTA1
Description		adrenoceptor alpha 1D	syntrophin alpha 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane	Intracellular Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Protein-containing Complex Sarcolemma Synapse
	Molecular Function	Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Identical Protein Binding	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Behavior Positive Regulation Of Cell Proliferation Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport
Pathways		Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs		Amphetamine Midodrine Cabergoline Dapiprazole Amitriptyline Alfuzosin Norepinephrine Mirtazapine Phenylephrine Promazine Prazosin Imipramine Chlorpromazine Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Phentolamine Ergotamine Tamsulosin Methoxamine Propiomazine Fenoldopam Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Carvedilol Doxepin Desipramine Terazosin Pergolide Bromocriptine Quetiapine Mephentermine Methotrimeprazine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Silodosin Droxidopa Xylometazoline Perospirone Dosulepin Etoperidone Cirazoline Synephrine Tiapride
Diseases			Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		Paneth cell defects in Crohn's disease ( 28352666) Preeclampsia ( 23551011) Sense of smell ( 26632684)	HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)
Interacting Genes		8 interacting genes: ADRA1A FLNC LNX1 NOS1 SNTA1 SNTB1 SNTB2 SNTG1	73 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6
Entrez ID		146	6640
HPRD ID		00079	03009
Ensembl ID		ENSG00000171873	ENSG00000101400
Uniprot IDs		B0ZBE0 P25100	Q13424
PDB IDs
Enriched GO Terms of Interacting Partners?
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