SNTA1 and KCNA4

Number of citations of the paper that reports this interaction (PubMedID 16637659)
25

Data Source:
BioGRID (unspecified method)
HPRD (in vitro)

		SNTA1	KCNA4
Description		syntrophin alpha 1	potassium voltage-gated channel subfamily A member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Protein-containing Complex Sarcolemma Synapse	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Dendritic Spine
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Ion Binding
	Biological Process	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways			Voltage gated Potassium channels
Drugs			Arginineamide Dalfampridine
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)	Diastolic blood pressure ( 27841878) Luteinizing hormone levels in polycystic ovary syndrome ( 26284813) Menarche (age at onset) ( 27182965) Polycystic ovary syndrome ( 26284813) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27841878)
Interacting Genes		73 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6	16 interacting genes: ACTN2 CASK DLG1 DLG2 DLG3 DLG4 DLGAP1 ERBIN KCNA2 LNX1 NDUFA4L2 NEU1 PATJ SAT1 SNTA1 SNTG1
Entrez ID		6640	3739
HPRD ID		03009	01444
Ensembl ID		ENSG00000101400	ENSG00000182255
Uniprot IDs		Q13424	P22459
PDB IDs
Enriched GO Terms of Interacting Partners?
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