ADRA1D and SNTB1

Number of citations of the paper that reports this interaction (PubMedID 18468998)
31

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		ADRA1D	SNTB1
Description		adrenoceptor alpha 1D	syntrophin beta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane	Intracellular Cytoplasm Cytoskeleton Focal Adhesion Dystrophin-associated Glycoprotein Complex Protein-containing Complex Sarcolemma Synapse
	Molecular Function	Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Identical Protein Binding	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding PDZ Domain Binding
	Biological Process	Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Behavior Positive Regulation Of Cell Proliferation Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway	Muscle Contraction
Pathways		Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs		Amphetamine Midodrine Cabergoline Dapiprazole Amitriptyline Alfuzosin Norepinephrine Mirtazapine Phenylephrine Promazine Prazosin Imipramine Chlorpromazine Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Phentolamine Ergotamine Tamsulosin Methoxamine Propiomazine Fenoldopam Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Carvedilol Doxepin Desipramine Terazosin Pergolide Bromocriptine Quetiapine Mephentermine Methotrimeprazine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Silodosin Droxidopa Xylometazoline Perospirone Dosulepin Etoperidone Cirazoline Synephrine Tiapride
Diseases
GWAS		Paneth cell defects in Crohn's disease ( 28352666) Preeclampsia ( 23551011) Sense of smell ( 26632684)	C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Cerebrospinal T-tau levels ( 28247064) Eye morphology ( 29921221) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29083408) JT interval (sulfonylurea treatment interaction) ( 27958378) Myopia (pathological) ( 23406873) Myopia (severe) ( 23933737) Periodontitis (CDC/AAP) ( 24024966) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thalamus volume ( 31530798)
Interacting Genes		8 interacting genes: ADRA1A FLNC LNX1 NOS1 SNTA1 SNTB1 SNTB2 SNTG1	12 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA KCNJ12 MAPK12 RPS6KA1 SCN4A SCN5A UTRN
Entrez ID		146	6641
HPRD ID		00079	02490
Ensembl ID		ENSG00000171873	ENSG00000172164
Uniprot IDs		B0ZBE0 P25100	Q13884
PDB IDs
Enriched GO Terms of Interacting Partners?
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