RDH12 and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RDH12	MAP1LC3A
Description		retinol dehydrogenase 12	microtubule associated protein 1 light chain 3 alpha
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Endoplasmic Reticulum Membrane Photoreceptor Inner Segment Membrane	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse
	Molecular Function	Retinol Dehydrogenase Activity Protein Binding NADP-retinol Dehydrogenase Activity	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Retinoid Metabolic Process Visual Perception Retinol Metabolic Process Photoreceptor Cell Maintenance Oxidation-reduction Process Cellular Detoxification Of Aldehyde	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision)	Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy
Drugs		Vitamin A
Diseases		Leber congenital amaurosis (LCR)
GWAS			Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241)
Interacting Genes		4 interacting genes: ANXA8L1 BUB1 MAP1LC3A RBPMS	49 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG101 ATG13 ATG4B BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV NBR1 NEDD4 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RB1CC1 RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TUBA4A ULK1
Entrez ID		145226	84557
HPRD ID		10585	03144
Ensembl ID		ENSG00000139988	ENSG00000101460
Uniprot IDs		A0A0S2Z613 Q96NR8	Q9H492
PDB IDs			3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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