CSF3R and WSB1

Number of citations of the paper that reports this interaction (PubMedID 17001306)
5

Data Source:
BioGRID (affinity chromatography technology, protein complementation assay)

		CSF3R	WSB1
Description		colony stimulating factor 3 receptor	WD repeat and SOCS box containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex	Intracellular Cytosol
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding Signaling Receptor Activity Granulocyte Colony-stimulating Factor Binding	Protein Binding
	Biological Process	Defense Response Cell Adhesion Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Regulation Of Myeloid Cell Differentiation Amelogenesis	Protein Polyubiquitination Biological_process Intracellular Signal Transduction Post-translational Protein Modification
Pathways		Other interleukin signaling Transcriptional regulation of granulopoiesis	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Pegfilgrastim Filgrastim FavId Lenograstim
Diseases
GWAS		Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Iron status biomarkers (total iron binding capacity) ( 28334935) Lymphocyte percentage of white cells ( 27863252) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Neutrophil percentage of white cells ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 27863252)	Birth weight ( 31043758) Chronic myeloid leukemia ( 21540461) Dental caries ( 23064961)
Interacting Genes		19 interacting genes: CISH CSF3 ELANE FTH1 GRB2 HCK INPP5D JAK1 JAK2 LCK LYN PLA2G1B PTPN11 SHC1 SOCS3 STAT3 SYK WSB1 WSB2	7 interacting genes: CSF3R DIO2 GSK3B HIPK2 LRRK2 UBE2D2 UBE2D3
Entrez ID		1441	26118
HPRD ID		00737	15680
Ensembl ID		ENSG00000119535	ENSG00000109046
Uniprot IDs		Q99062	A0A024QZ36 A0A024QZ51 Q8NC76 Q9Y6I7
PDB IDs		1AZ7 2D9Q
Enriched GO Terms of Interacting Partners?
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