WSB1 and DIO2

Number of citations of the paper that reports this interaction (PubMedID 15965468)
87

Data Source:
BioGRID (enzymatic study)

		WSB1	DIO2
Description		WD repeat and SOCS box containing 1	iodothyronine deiodinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Cytosol	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Thyroxine 5'-deiodinase Activity Selenium Binding Ubiquitin Protein Ligase Binding Thyroxine 5-deiodinase Activity
	Biological Process	Protein Polyubiquitination Biological_process Intracellular Signal Transduction Post-translational Protein Modification	Selenocysteine Incorporation Thyroid Hormone Generation Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Brown Fat Cell Differentiation Oxidation-reduction Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Regulation of thyroid hormone activity
Drugs
Diseases
GWAS		Birth weight ( 31043758) Chronic myeloid leukemia ( 21540461) Dental caries ( 23064961)	Free thyroxine concentration ( 30367059) Metabolite levels ( 23823483) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Rosacea symptom severity ( 29771307)
Interacting Genes		7 interacting genes: CSF3R DIO2 GSK3B HIPK2 LRRK2 UBE2D2 UBE2D3	6 interacting genes: MARCHF6 UBE2G1 UBE2J1 USP20 USP33 WSB1
Entrez ID		26118	1734
HPRD ID		15680	09027
Ensembl ID		ENSG00000109046	ENSG00000211448
Uniprot IDs		A0A024QZ36 A0A024QZ51 Q8NC76 Q9Y6I7	A8K845 Q92813
PDB IDs
Enriched GO Terms of Interacting Partners?
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