DUSP19 and PTK7

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		DUSP19	PTK7
Description		dual specificity phosphatase 19	protein tyrosine kinase 7 (inactive)
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Kinase Inhibitor Activity MAP-kinase Scaffold Activity Protein Binding JUN Kinase Phosphatase Activity Protein Kinase Activator Activity Mitogen-activated Protein Kinase Kinase Kinase Binding	Protein Kinase Activity Protein Binding ATP Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Negative Regulation Of Protein Kinase Activity Activation Of Protein Kinase Activity Peptidyl-tyrosine Dephosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Negative Regulation Of JUN Kinase Activity Positive Regulation Of Protein Kinase Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade	Establishment Of Planar Polarity Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778)
Interacting Genes		18 interacting genes: ALK EGFR EPHA2 EPHB6 ERBB2 ERBB3 ERBB4 FLT4 IGF1R INSR KDR LMTK2 MAP2K7 MAP3K5 MAPK9 PTK7 ROR1 ROR2	32 interacting genes: CDC14A CLNK CTDSP2 DUPD1 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 ERBB2 ILKAP MTMR1 MTMR10 MTMR6 MTMR9 PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		142679	5754
HPRD ID		13254	03534
Ensembl ID		ENSG00000162999	ENSG00000112655
Uniprot IDs		Q8WTR2	Q13308
PDB IDs		3S4E 4D3P 4D3Q 4D3R
Enriched GO Terms of Interacting Partners?
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