PTK7 and CTDSP2

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		PTK7	CTDSP2
Description		protein tyrosine kinase 7 (inactive)	CTD small phosphatase 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Nucleoplasm
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding
	Biological Process	Establishment Of Planar Polarity Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation IRE1-mediated Unfolded Protein Response Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Height ( 31562340) Metabolite levels ( 23823483) Trochanter size ( 31053729)
Interacting Genes		32 interacting genes: CDC14A CLNK CTDSP2 DUPD1 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 ERBB2 ILKAP MTMR1 MTMR10 MTMR6 MTMR9 PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	11 interacting genes: AKT1 AR CDCA3 CSF1R EPHA1 EPHA3 INSRR POLR2A PTK7 SNAI1 TYRO3
Entrez ID		5754	10106
HPRD ID		03534	12281
Ensembl ID		ENSG00000112655	ENSG00000175215
Uniprot IDs		Q13308	A0A024RB65 A0A024RBA6 O14595
PDB IDs			2Q5E
Enriched GO Terms of Interacting Partners?
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