COL4A5 and MATN2

Number of citations of the paper that reports this interaction (PubMedID 12180907)
12

Data Source:
HPRD (in vitro)

		COL4A5	MATN2
Description		collagen type IV alpha 5 chain	matrilin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix	Basement Membrane Extracellular Space Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Neuron Migration Growth Plate Cartilage Chondrocyte Morphogenesis Axon Guidance Biological_process Glial Cell Migration Dendrite Regeneration Response To Axon Injury
Pathways		Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs
Drugs
Diseases		Alport syndrome
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Diffusing capacity of carbon monoxide ( 30694715) Erectile dysfunction ( 30583798)
Interacting Genes		19 interacting genes: ANTXR2 ANXA7 APP CD93 CDKN1A DAZAP2 DCN FBLN2 FN1 GLA HABP2 MATN2 MMP9 NR1H2 OSM RNF10 SERPINE2 SMN1 TK1	17 interacting genes: ATXN1 ATXN1L ATXN7 CACNA1A CBFA2T3 COL1A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 DVL3 FBN2 FN1 MATN1 MATN4
Entrez ID		1287	4147
HPRD ID		02363	03660
Ensembl ID		ENSG00000188153	ENSG00000132561
Uniprot IDs		A7MBN3 P29400 Q49AM6	A0A140VKH7 O00339 Q8N2G3
PDB IDs		5NAZ
Enriched GO Terms of Interacting Partners?
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