HEXIM2 and ZNF250

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		HEXIM2	ZNF250
Description		HEXIM P-TEFb complex subunit 2	zinc finger protein 250
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Nucleus
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding	DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Asthma ( 31619474) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)	Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		15 interacting genes: CCNT1 CDK9 GATA1 IHO1 MEOX2 PIM1 PIN1 PRDM14 RNPS1 SPRY1 SPRY2 TADA3 TERF1 TERF2 ZNF250	47 interacting genes: BEGAIN CARD9 CCDC102B CCDC136 CCDC85B CDCA7L CEP44 DPPA2 DVL2 FAM124A GMCL1 GNPTAB GOLGA2 HEXIM2 HOOK1 HOOK2 KASH5 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 LDOC1 LZTS2 MAGOHB MID2 MTUS2 NINL PLEKHF2 PRPF31 SSX2IP SYNE4 TFF1 TMCC2 TNNT1 TNS2 TRAF1 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB8A ZC4H2 ZNF165 ZNF175 ZNF460 ZNF473
Entrez ID		124790	58500
HPRD ID		08129	15758
Ensembl ID		ENSG00000168517	ENSG00000196150
Uniprot IDs		Q96MH2	B3KNS9 P15622
PDB IDs
Enriched GO Terms of Interacting Partners?
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