HEXIM2 and TADA3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HEXIM2	TADA3
Description		HEXIM P-TEFb complex subunit 2	transcriptional adaptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	SAGA Complex Intracellular Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex STAGA Complex Transcription Factor TFTC Complex Mitotic Spindle
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding	Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated	Mitotic Cell Cycle Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Protein Deubiquitination Intracellular Estrogen Receptor Signaling Pathway Regulation Of Histone Deacetylation Regulation Of Protein Stability Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Tubulin Deacetylation
Pathways			HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Asthma ( 31619474) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)
Interacting Genes		15 interacting genes: CCNT1 CDK9 GATA1 IHO1 MEOX2 PIM1 PIN1 PRDM14 RNPS1 SPRY1 SPRY2 TADA3 TERF1 TERF2 ZNF250	29 interacting genes: ADPGK ANKRD12 AR CCNC EIF3J EP300 ESR1 FAM107B H3-4 HEXIM2 HSPA8 ING5 KDM1A MAGEH1 MFHAS1 NR1I2 PIAS4 RARA RFX1 RXRA RXRB SAP18 SGF29 TADA2A TP53 TXNRD2 USP5 XRCC6 ZNF7
Entrez ID		124790	10474
HPRD ID		08129	04252
Ensembl ID		ENSG00000168517	ENSG00000171148
Uniprot IDs		Q96MH2	A0A024R2D7 A8K899 O75528
PDB IDs
Enriched GO Terms of Interacting Partners?
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