FRMD6 and YWHAB

  • Number of citations of the paper that reports this interaction (PubMedID 15324660)
  • 174
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

FRMD6

YWHAB

Description FERM domain containing 6 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anticoagulant levels ( 22216198)
  • Brain structure ( 20171287)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Hippocampal atrophy ( 19668339)
  • Lung cancer (smoking interaction) ( 24658283)
  • Multiple sclerosis ( 31604244)
  • Nonsyndromic cleft lip with or without cleft palate ( 28087736)
  • Total ventricular volume ( 21116278)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes 20 interacting genes: - BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LZTS2 MED4 MID2 MLH1 RASSF8 SSX2IP SUV39H1 TCF12 TSC22D4 WDR7 YWHAB 144 interacting genes: ABL1 ADAM22 AFDN AKAP13 ALS2 APP ATP5F1A BAD BAX BCL2L11 BCR BID BRAF C1QBP CAMK2A CAMK2B CBL CDC25A CDC25B CDC25C CDK11B CDK14 CDKN1B CHAF1A CRTC2 CSNK2A1 DAPK1 DCAF7 DHX15 DYRK1A EDC3 EGFR EPB41 EPB41L1 EPB41L3 ERRFI1 EXO1 FER FRMD6 GAPVD1 GEM H3C1 HDAC5 HES1 HSP90AB1 HSPA1A HSPA1B HSPA5 HSPB1 IGF1R IKBKB ING1 INSR IRS1 IRS2 ITGB1 ITGB4 KANK1 KCNK15 KCNK3 KCNK9 KIAA0930 KIF1C KIF23 KIF5B KLC1 KRT18 LARP1 LRRK2 LYST MAP3K3 MAPK7 MAPT MARK2 MARK4 MDM4 MICALL1 MINK1 MLXIP MPRIP MST1R MTNR1A MTNR1B OSBPL3 PARD3 PARD6B PDCL2 PDE3B PI4KB PIK3R2 PIK3R4 PRKCD PRKCG PRKCZ PRPF6 PTPN3 RABGEF1 RACGAP1 RADIL RAF1 RAI14 RALGPS2 RASGRF1 RGS3 RGS7 RIN1 RIOK1 RMDN3 RNPS1 RPS6KA1 SAMSN1 SKP2 SLC4A7 SLC8A1 SLC8A2 SLC8A3 SLC9A1 SNCA SNRNP200 SON SRC SRRM2 SRSF10 SRSF3 STK38 STK38L TESK1 TESK2 TH TJP2 TNFAIP3 TPD52L1 TSC1 TSC2 TUBB UBC UCP2 UCP3 WDR77 WEE1 YWHAE YWHAG ZFP36 ZFP36L1
Entrez ID 122786 7529
HPRD ID 12646 03184
Ensembl ID ENSG00000139926 ENSG00000166913
Uniprot IDs Q96NE9 P31946 V9HWD6
PDB IDs 2BQ0 2C23 4DNK 5N10 6A5Q 6BYK 6GN0 6GN8 6GNJ 6GNK 6GNN 6HEP
Enriched GO Terms of Interacting Partners?
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