RAB39B and RUFY1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RAB39B	RUFY1
Description		RAB39B, member RAS oncogene family	RUN and FYVE domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Golgi Apparatus Plasma Membrane Endomembrane System Cytoplasmic Vesicle Membrane Vesicle Neuron Projection	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin V Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Autophagy Regulation Of Autophagy Vesicle-mediated Transport Rab Protein Signal Transduction Synapse Organization	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Synthesis of PIPs at the plasma membrane
Drugs
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS			Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730)
Interacting Genes		5 interacting genes: GOLGA2 RAB3GAP1 RUFY1 SGSM3 ZDHHC17	16 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TXNDC17 UTP25
Entrez ID		116442	80230
HPRD ID		06703	15282
Ensembl ID		ENSG00000155961	ENSG00000176783
Uniprot IDs		Q96DA2	A8K7B1 Q96T51
PDB IDs			2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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