RUFY1 and AP3D1

Number of citations of the paper that reports this interaction (PubMedID 23144738)
10

Data Source:
BioGRID (pull down, affinity chromatography technology)

		RUFY1	AP3D1
Description		RUN and FYVE domain containing 1	adaptor related protein complex 3 subunit delta 1
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GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Cell Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane AP-3 Adaptor Complex Terminal Bouton Postsynapse Presynaptic Endosome Glutamatergic Synapse Axon Cytoplasm
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Protein Targeting To Vacuole Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Melanosome Organization Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730)	Height ( 28552196 31562340) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Myocardial infarction ( 24916648) Pulse pressure ( 30578418) Red blood cell count ( 27863252) Systolic blood pressure ( 30578418)
Interacting Genes		16 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TXNDC17 UTP25	10 interacting genes: AP3B1 AP3S1 AP3S2 ARF1 ARF6 CCN2 RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		80230	8943
HPRD ID		15282	06260
Ensembl ID		ENSG00000176783	ENSG00000065000
Uniprot IDs		A8K7B1 Q96T51	O14617
PDB IDs		2YQM 2YW8	4AFI
Enriched GO Terms of Interacting Partners?
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