RAB39B and RAB3GAP1

Number of citations of the paper that reports this interaction (PubMedID 16923123)
61

Data Source:
BioGRID (two hybrid)

		RAB39B	RAB3GAP1
Description		RAB39B, member RAS oncogene family	RAB3 GTPase activating protein catalytic subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Golgi Apparatus Plasma Membrane Endomembrane System Cytoplasmic Vesicle Membrane Vesicle Neuron Projection	Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Protein-containing Complex Extracellular Exosome Endoplasmic Reticulum Tubular Network Postsynapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin V Binding	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Autophagy Regulation Of Autophagy Vesicle-mediated Transport Rab Protein Signal Transduction Synapse Organization	Brain Development Positive Regulation Of Gene Expression Hypothalamus Development Lipid Droplet Organization Camera-type Eye Development Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Short-term Neuronal Synaptic Plasticity Excitatory Postsynaptic Potential Face Morphogenesis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Positive Regulation Of Protein Lipidation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Autophagosome Assembly
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	COPI-independent Golgi-to-ER retrograde traffic RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)	Warburg micro syndrome Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS			Blood metabolite levels ( 24816252) Body mass index ( 25673413) Cholesterol, total ( 24097068 25961943 20686565) Corneal structure ( 21979947) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		5 interacting genes: GOLGA2 RAB3GAP1 RUFY1 SGSM3 ZDHHC17	8 interacting genes: FEZ1 FEZ2 RAB22A RAB39A RAB39B RAB3GAP2 RPH3AL WDR7
Entrez ID		116442	22930
HPRD ID		06703	16002
Ensembl ID		ENSG00000155961	ENSG00000115839
Uniprot IDs		Q96DA2	B9A6J2 Q15042
PDB IDs
Enriched GO Terms of Interacting Partners?
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